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SARM Antibody
SARM Antibody
產品編號: 6917
規  格:
單  價: 詢價
生 產 商: ProSci
到貨時間: 2-3weeks
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BACKGROUND
SARM Antibody: Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. SARM (SAM and ARM-containing protein), along with other molecules such as TIRP, TRIF, TIRAP, and MyD88, is thought to serve as an adaptor protein for the TLRs that allows for the activation of downstream kinases and NF-κB, and ultimately the expression of proteins involved in host defense. While SARM has not been conclusively shown to associate directly with TLRs, the presence of a Toll-interleukin-1 (TIR) domain in SARM is consistent with a role as a signaling molecule.

ALTERNATE NAMES
SARM Antibody: SARM, SAMD2, MyD88-5, KIAA0524, SARM, Sterile alpha and TIR motif-containing protein 1, Sterile alpha and Armadillo repeat protein

CONJUGATE
Unconjugated

PURIFICATION
SARM Antibody is affinity chromatography purified via peptide column.

HOST SPECIES
Rabbit

CLONALITY
Polyclonal

ISOTYPE
IgG

IMMUNOGEN
At least three alternatively spliced transcript variants encoding distinct isoforms have been observed. SARM antibody recognize the longest isoform.

TESTED APPLICATIONS
SARM antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human SARM.

APPLICATIONS
E, WB, IF

BUFFER
SARM antibody can be used for detection of SARM by Western blot at 1 - 2 μg/mL. For immunofluorescence start at 20 μg/mL.

STORAGE CONDITIONS
SARM antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

SPECIES REACTIVITY
Human, Mouse, Rat
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